Tuscumbia Homes for Sale

Welcome to Tuscumbia, Missouri – a charming town nestled in the heart of Miller County. With its rich history, friendly community, and picturesque landscapes, Tuscumbia embodies the essence of small-town living. Whether you’re drawn to its serene surroundings or the warm hospitality of its residents, this quaint town has something for everyone.

Tuscumbia is conveniently located near the beautiful Lake of the Ozarks, making it a perfect spot for outdoor enthusiasts. Enjoy fishing, boating, and hiking in the nearby state parks, or take a leisurely stroll through the town's scenic streets, where you can admire the historic architecture and lush greenery. With a population that values community spirit, Tuscumbia offers a peaceful environment that’s ideal for families, retirees, and anyone looking to escape the hustle and bustle of city life.

As for homes for sale, Tuscumbia boasts a variety of options that cater to different lifestyles and budgets. From charming historic homes that reflect the town's rich heritage to modern constructions equipped with contemporary amenities, you’ll find the perfect residence to call your own. The real estate market here is vibrant, providing opportunities for first-time homebuyers and seasoned investors alike.

Explore the possibilities of living in Tuscumbia, where you can enjoy a tranquil lifestyle without sacrificing access to essential amenities. Discover your dream home in this delightful town, and embrace the warm, welcoming community that awaits you!

Newest Tuscumbia Homes for Sale

$749,000

3 Beds ⋅ 2 Baths ⋅ 3588803 MLS

Escape the noise and embrace ultimate freedom in peaceful Tuscumbia, MO. This stunning 4,000-square-foot "Shouse" (shop-house) sits on 90 expansive acres of pristine land, offering a rare combination of modern country living and unmatched versatility—with absolutely no HOA or property restrictions. The property features a beautifully designed 1,500-square-foot living quarters, offering a highly functional 3-bedroom, 2-bathroom layout with a modern open floor plan and bright interiors perfect for comfortable country living. Seamlessly attached is a massive 2,500-square-foot premium shop space, providing a clear-span canvas ready for a home business, heavy equipment, boat or RV storage, or the ultimate workshop setup. Beyond the structure, the land itself boasts a spectacular, panoramic view of the winding Osage River. With 90 acres to your name, you will enjoy unparalleled privacy, abundant local wildlife, and total freedom to hunt, farm, build, or expand exactly as you see fit. Whether you are looking for a private homestead, a workspace for your passion projects, or a scenic river-view retreat, this unique property delivers the unrestricted lifestyle you’ve been dreaming of.

1805 HWY 52, Tuscumbia

$765,000

1 Beds ⋅ 2 Baths ⋅ 3586318 MLS

This 154.5 +- acre property in Miller County, Missouri presents an opportunity for recreational use, hunting, and also offering great Airbnb potential. Located approximately 10 minutes from Eldon and about 20 minutes from the Lake of the Ozarks area, the property offers a combination of seclusion and accessibility to nearby towns, services, and recreational amenities. The land is primarily timbered and is characterized by long, winding ridge systems that extend throughout the property. These ridges, along with the surrounding hills and hollers, create varied terrain and elevation changes that contribute to the overall layout of the tract. The natural topography may influence wildlife movement and provides a range of opportunities for outdoor activities such as hunting, hiking, and exploring. Established trails are present throughout much of the property, allowing for access by ATV or utility vehicle and supporting both recreational use and land management. In addition to this outstanding tract of land, the cabin comes furnished with everything that is currently in it, and a 30 x 40 shop also await the new buyers.

18 Brown Road, Tuscumbia

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Listing information is provided courtesy of the Broker Reciprocity/IDX of Bagnell Dam Association of REALTORS® and Lake of the Ozarks Board of REALTORS®, Inc. Multiple Listing Services. Copyright 2026 Multiple Listing Service, Inc. of Bagnell Dam Association of REALTORS® MLS, Inc. and Lake of the Ozarks Board of REALTORS® MLS, Inc. Information is being provided for consumers’ personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Information herein is believed to be accurate and timely, but no warranty as such is expressed or implied. 2026 RE/MAX Lake of the Ozarks